2009 YSP Teacher and Researcher Partnership Program

Dr. Edwin Antony (Ellenberger lab) and science teacher David Allchurch, Central VPA High School, are participants in the Teacher and Research Program (TRP), a branch of the Young Scientist Program at Washington University. David is investigating how the Srs2 helicase (a protein involved in regulating the Homologous Recombination DNA Repair Pathway) unwinds DNA. Qi Xiao, a former YSP student working this summer in the Ellenberger lab, was instrumental in uncovering the mechanism of how Srs2 negatively regulates Homologous Recombination (Antony et al, Mol Cell, 2009), and is currently working on solving crystal structures of the Srs2-Rad51 protein complex.